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Malabsorption issues due to gastrointestinal conditions

Body weight-based dosing (mcg/kg) is sometimes proposed in peptide compounding circles, but no published study supports any specific mcg/kg target for AOD-9604 in adolescents

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Malhotra 2024 in NEJM (PMID 38912654) reported on obstructive sleep apnea + obesity (SURMOUNT-OSA), with tirzepatide reducing the apnea-hypopnea index by approximately 27.4 events per hour at 52 weeks alongside the expected weight reductions