tirzepatide 5.0 mg Unlikely to Exacerbate DR in First Year of Treatment Mounjaro Tirzepatide 5mg Injection -

Everyone in this study also had established cardiovascular disease, so I would not assume the same size of benefit in people with diabetes who do not already have heart problems

These negative results may be due to limitations imposed by protein overexpression or reflect TMEM55Bs primary role in regulating TBC1D9B function, for example, by conformationally activating TBC1D9B to facilitate its catalytic activity

Cell Metabolism, 22 (1), 31

A doctor can help decide which option matches the underlying cause

While its a very small volume, for protocols requiring extreme precision with micro-doses, some researchers account for this or use special low-dead-space syringes to minimize it