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Potential complementary evidence of GLP-1RAs and SGLT2is In a meta-analysis comparing the effects of GLP-1RAs with SGLT2is, five GLP-1RA (ELIXA, LEADER, SUSTAIN-6, EXSCEL, and Harmony Outcomes) and three SGLT2i trials (EMPA-REG OUTCOME, CANVAS Program, and DECLARE-TIMI 58) with a total of 77,242 patients were include [35]
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This is a mechanism-level description of a research compound, not a statement of proven clinical benefit in humans
Plant Cell 16 , 31323147 (2004)
MOTS-c activates AMPK more acutely through folate cycle disruption and AICAR accumulation
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