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Never discontinue semaglutide without medical guidance, as abrupt cessation may affect glycemic control in patients with diabetes
Common gastrointestinal adverse effects associated with semaglutide include: Nausea (reported in up to 44% of patients on Wegovy, 20% on Ozempic, and 15% on Rybelsus) [2] [4] Vomiting Diarrhea Constipation Abdominal pain or discomfort Dyspepsia These effects are typically dose-dependent and most pronounced during the initial titration phase, with higher rates observed at weight management doses compared to diabetes doses
In addition to describing conserved motifs typical of each class, we have paid attention to the presence of N- and C-terminal extensions or of sequence insertions
If possible, get a body composition assessment (DEXA scan or bioelectrical impedance)
Above, we summarized the peptides research-backed benefits and side effects, and illuminated worthwhile directions for future research
