GLP-1 Uses Under Investigation GLP-1s for Addiction Soon after GLP-1s became available for diabetes and then weight loss, users began anecdotally reporting fewer cravings for things like cigarettes and alcohol and less desire to engage in compulsive activities like shopping or gambling
Compared with the NC group, animal experiments found that the serum aspartate transaminase (AST), alanine transaminase (ALT), total cholesterol (TC), and TG were increased in the HF group, and the level of liver TG was also increased
The Problem With GLP-1 Agonists Among the most concerning claims are reports of gastroparesis, a debilitating condition characterized by stomach paralysis, which can lead to chronic nausea, vomiting, diarrhea, bowel blockages, dangerous malnutrition, and other health issues
2.01 ml/min/1.73 m 2
As discussed above, this function of GLP-1R could be partially attributed to its role in regulating glucose metabolism to inhibit lactate overproduction