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Narasimhan K, Ramanadham S, Rohrich RJ

Moreover, SCFAs such as acetate can remodel macrophage glycolysis, activate the hypoxia-inducible factor 1 (HIF-1) axis and NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome, thereby increasing interleukin-1 (IL-1) and nitric oxide production and enhancing pulmonary innate immunity (Machado et al., 2022)

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