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While these compounds have been studied for antioxidant activity in laboratory settings, robust clinical evidence specifically supporting skin benefits in humans is limited

Clinical Evidence: Semaglutide and Cardiovascular Blood Pressure Outcomes The SUSTAIN-6 trial, which followed over 3,000 patients with type 2 diabetes, documented that weekly semaglutide reduced the risk of major adverse cardiovascular events by 26% compared to placebo

However, it is worth noting that the extent of the increase and the duration for which these elevated levels are maintained could vary between the two

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