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10.1155/2020/5230716 32 SedlakL.ZychM.WojnarW.Wygledowska-PromienskaD
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Direct scavenging of free radicals (especially ROS), inhibition of ROS manufacturing enzymes, and preservation of mitochondrial integrity and function affect redox signaling by activating nuclear factor erythroid-derived 2-like 2 (Nrf2) and peroxisome proliferator-activated receptor alpha (PPAR), and the synthesis of heat shock proteins (HSPs), thioredoxins, sirtuins, and other antioxidant molecules are pathways through which L-carnitine and its derivatives modulate oxidative stress conditions [14, 38]
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When administered into the affected joint, Cingal restores lubrication and cushioning through the HA in the injections
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