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Patients with pre-existing eye conditions such as glaucoma, cataracts, or previous episodes of optic nerve inflammation should be carefully evaluated before starting tirzepatide therapy

Some people tolerate one medicine better than another

They have been known to trigger attacks in sensitive individuals (WebMD)

Recognizing that the STEP-8 population may not fully represent the Greek obesity population, trial-based characteristics were reviewed and adapted using local epidemiological data and expert clinical opinion (e.g., smoking prevalence, hypertension, and diabetes distribution) to enhance relevance for the Greek setting