J Clin Investig 53(3):841847
PachecoBPCrajoinasROCoutoGKDavelAPLessaLMRossoniLVet al
Quick Take (TLDR) Mostly animal and in vitro data plus multiple very small uncontrolled human reports (knee pain case series n=16, interstitial cystitis pilot n=12, 2subject IV infusion) and no randomized controlled trials or published human pharmacokinetic profiles
BREAKING NEWS APRIL 15, 2026 - In a welcome announcement to the SSRP community, the FDA reported today that it will imminently remove the following bulk drug substances from category 2: BPC-157, LL-37, DiHexa, DSIP, Epitalon, *GHK-Cu (injectable only), KPV, PEG-MGF, Melanotan II, MOTs-C, Semax, and TB-500
Maintain reconstituted vials at cold temperatures for maximum stability