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In rodent and cell work, NNMT knockdown or inhibition has been described as protecting against diet-induced weight gain and improving metabolic measures without reducing food intake [5] [6]

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Gastrointestinal absorption barriers of vitamin B 12 can be avoided by intramuscular injection

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Spending money on high-dose B12 pills for this purpose is unlikely to be beneficial and should not replace evidence-based weight management approaches