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In the SURMOUNT-2 study, which involved 938 adults with obesity or overweight and T2D, tirzepatide showed significant weight loss effects of 13.4% and 15.7% for the 10 and 15 mg doses, respectively, with over 80% of participants experiencing at least a 5% weight loss [92]

On the next day, mice were given a single dose of oral gavage of 2.5 g/kg b.wt

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(accessed February 2025) 18GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued

English PJ, Ghatei MA, Malik IA, Bloom SR, Wilding JP