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Side Effect Profiles The most noticeable practical difference is that dual agonists like tirzepatide tend to cause slightly more gastrointestinal side effects than pure GLP-1 agonists
Some research has also indicated that GLP-1 can raise the risk of acute pancreatitis, or inflammation of the pancreas
The peptide itself only accounts for part of the equation
Sengupta et al., 2006
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