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However, when intracellular iron ions are overloaded, Fe 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Ingold et al., 2018) (Figure 4)

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Polymorphic transitions in single crystals: a new molecular dynamics method

This synergistic pattern suggests that neither amino acid functions as an isolated therapeutic agent