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Furthermore, the observed effects could be mediated by other unmeasured biological or lifestyle factors

The best choice depends on the specific application, and many researchers combine multiple peptides for comprehensive coverage

2025;257:110421.[DOI] 129

MPP + treatment significantly reduces TIGAR expression in HT22 cells, downregulates NADPH, GPX4, and GSH levels, upregulates GSSG levels and the GSSG/GSH ratio, decreases adenosine triphosphate (ATP) production, and promotes neuronal ferroptosis, iron-dependent lipid peroxidation, and mitochondrial dysfunction, thereby exacerbating neuronal cytotoxicity

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