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Evans CS, Holzbaur EL
In metabolic dysfunctionassociated steatohepatitis (MASH), for example, it remains uncertain whether improvements in hepatic inflammation and fibrosis are exclusively secondary to weight loss and metabolic improvements, or whether direct hepatoprotective mechanisms are involved
This showed up in trials where patients lost weight, paving the way for the development of these drugs for obesity as well
GLP-1 receptor agonists and overall cancer risk in adults with obesity
Additionally, ghrelin administration has been found to increase food consumption in some individuals, although further research is needed to fully understand its effects
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