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Enzymatic antioxidant defense cannot rely solely on SOD, because that would result in markedly increased tissue damage due to high accumulated levels of intracellular H 2 O 2 , the substrate for production of OH via the Fenton reaction

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Choline and methionine help move fat out of the liver, supporting healthy liver function

Based on the previous redox titrations (Figure 3B) and an E of -330 mV for DTT, this corresponds to a cytosolic redox potential in wild-type yeast of approximately -300 mV