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doi:10.1016/j.cbi.2018.08.023 Zamek-Gliszczynski MJ, Hoffmaster KA, Nezasa K, Tallman MN, Brouwer KL
This aggregation is accompanied by the loss of iron-sulfur cluster proteins, which ultimately triggers mitochondrial protein toxicity stress and energy metabolism collapse (124126)
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These may include chronic liver problems, diabetes, some lung diseases, and neurodegenerative disorders
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