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Although transcriptional analysis of AITC-treated seedlings revealed down-regulation of many auxin-inducible genes, auxin marker lines exposed to AITC did not indicate a change in auxin response and auxin-resistant mutants did not reveal an altered resistance to AITC 74

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The procognitive effect was then traced to the hepatocyte growth factor system and its receptor c-Met, with the synaptogenesis reported as dependent on HGF/c-Met activation (Benoist et al., J Pharmacol Exp Ther 2014)

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