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The strongest practical message is cautious optimism
If the CSP is invalid, it makes Novos decision not to maintain the patent questionable, to say the least, as it is losing two additional years of exclusivity on the Canadian market
But knowing the causes matters more, because causes are what you can actually control
The proteolytic processing of VEGFA by matrix metalloproteinases (MMPs) is crucial for the generation of biologically active fragments 12
Pharmaceutics 17(8):1004, 2025
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