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284,285 Importantly, these models can delineate minimal intervention setscombinatorial target nodes whose simultaneous inhibition is predicted to destabilize the network attractor state, thereby precluding adaptive escape and restoring therapeutic vulnerability
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GAS6/AXL signaling pathway The GAS6/AXL axis, a key member of the TAM (TYRO3, AXL, MERTK) receptor tyrosine kinase family, is frequently overactivated in solid tumors and is strongly associated with therapy resistance
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