A total of 1,961 adult participants with a BMI of at least 30 or at least 27 with at least one weight-related comorbidity were randomized to receive either semaglutide (2.4 mg) or placebo, administered subcutaneously once weekly, along with lifestyle intervention
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In addition, dysregulated or impaired autophagy has been associated with cardiovascular diseases such as atherosclerosis [16], cardiomyopathy [17], heart failure [18], and hypoperfusion injury [19]
Kryukov EV, Ivanov AV, Karpov VO, Vasilevich Alexandrin V, Dygai AM, Kruglova MP, et al