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The differences between peptides and other research compounds also matter, since the specificity and generally favorable safety profiles of peptides distinguish them from broader-acting molecules
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Although earlier studies did not show the interaction between S100A2 and RAGE, recent studies showed a micromolar affinity and strict calcium-dependent interaction between S100A2 and RAGE via the V-domain of RAGE (64) ( Figure 3 )
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Researchers should carefully weigh the advantages and disadvantages of both classes of research chemicals before incorporating either into their research
