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Published in 1982 the additional sequence appeared to code for a peptide that resembled GIP which in the meantime had been shown to boost glucagon (Lund, Goodman, Dee, Habener
Shashank Deshpande, Head of Human Pharma at Boehringer said: Survodutide has the potential to be the first global glucagon/GLP-1 dual agonist to help the more than 1 billion people living with obesity and MASH. Roche made headway earlier this year in advancing its injectable GLP-1/GIP receptor agonist CT-388 for obesity, while also demonstrating benefit for pre-diabetic patients
For more on side-effect management, see our semaglutide nausea relief guide
Semaglutide and SGLT2 inhibitors appear to work through different but complementary pathways, and recent trial data suggest their benefits may be additive when used together