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Oral versions must go through the digestive system and face barriers (acid, enzymes, food timing) which can reduce the amount of active drug reaching circulation
A Renewed Look at an Old Controversy The 2025 J Clin Med: The Cleanest Lens Yet The 2025 Am J Gastroenterology: Better Outcomes, Not Worse The 2025 Diabetes Metabolism: Even Safe After Prior Pancreatitis Historical Context: The Arc of Evidence Why the Myth Persisted Clinical Implications: How to Translate This in Practice Illustrative Cases Summary Table A Balanced Perspective Read More To view or add a comment, sign in Interesting post hoc analysis in Nature Medicine showing that remission of prediabetes even without weight loss can significantly reduce long-term risk of type 2 diabetes
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Topiramate modulates GABA receptors and sodium channels, enhancing satiety through pathways that scientists still do not fully understand
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