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Name: does semaglutide lower your a1c cardiovascular outcomes align more closely with attained dose than achieved weight loss Semaglutide and A1C Control: Lower
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The gradual dose titration schedule recommended in the prescribing information is specifically designed to minimize these gastrointestinal effects

Pregnant patients or those planning pregnancy should not use either medication, though the reasoning differs (Metformin for potential effects on fetal development, Retatrutide due to insufficient safety data)