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(2016) showed that metformin protects platelet mitochondria by inhibiting complex I activity, thereby reducing mitochondrial hyperpolarization, ROS generation, and mtDNA release, and consequently preventing mtDNA-mediated platelet activation via the dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN)-dependent pathway (Xin et al., 2016)

Adems, esta hormona retrasa el vaciado del estmago, lo que prolonga la sensacin de saciedad