10.1016/j.gene.2017.03.005 168 WangJ
Last reviewed: June 29, 2026 Last updated: June 29, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Research Context & Areas of Scientific Interest In laboratory and preclinical settings, GHK-Cu has been studied for its involvement in: Copper-mediated biochemical pathways Cellular signaling and regulatory mechanisms Gene expression models in controlled environments Extracellular matrix interaction dynamics Molecular modeling involving peptide-metal complexes Cellular response behavior in in-vitro systems These observations originate from preclinical and laboratory research only and do not represent clinical or cosmetic effects in humans
Dietary supplementation of mice with BB was shown to produce both TMA and TMAO, and to accelerate atherosclerosis, but only in the presence of gut microbiota (26)
Bolke L, Schlippe G, Ger J, et al