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Loss-of-function GSTM2 mouse model demonstrated that GSTM2 protected mice from excess fat accumulation

The challenge comes at higher doses

Biagi E, Rousseau R, Yvon E, Schwartz M, Dotti G, Foster A, Havlik-Cooper D, Grilley B, Gee A, Baker K, Carrum G, Rice L, Andreeff M , Popat U, Brenner M