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Anticipated Costs Post-Approval While neither compound has reached market, pricing for similar medications provides context: Semaglutide (Wegovy) Approximately $1,300-$1,500 monthly without insurance Tirzepatide (Zepbound) Approximately $1,000-$1,200 monthly without insurance Cagrilintide and retatrutide would likely fall in similar price ranges, with combination therapy potentially costing $2,000-$3,000 monthly without insurance coverage
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(PubMed) Lawson LD
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NCT04184622 ), and in SURPASS-2 it outperformed semaglutide on glucose and weight endpoints in type 2 diabetes ( Fras et al., NEJM 2021 )
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