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The heterogeneity of MCAS, with its varied mutational profiles and aberrant expression of hundreds of potent mediators, creates chronic multisystem polymorbidity with inflammatory, allergic, and dystrophic phenotypes
Nature 2009
Walter et al., 1996
CDMOs with a global footprint are particularly well-positioned to navigate this landscape, as they often have established relationships with regulators and a proven track record of compliance across multiple jurisdictions
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