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NFE2-related transcription factor 2 coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland

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While the relevance of these findings to humans remains uncertain, the potential risk necessitates avoiding tirzepatide in patients with known susceptibility to these rare thyroid malignancies

Pasternak, Albert-Ludwigs-University of Freiburg, Germany Copyright 2013 Aller, Rouhier and Meyer

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