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For individuals with polycystic ovary syndrome (PCOS) or insulin resistance, GLP-1 therapy before pregnancy can actually improve fertility outcomes by reducing insulin levels and restoring ovulatory cycles
Silver, H.J
Could this drug appear in my breast milk, and what are the expected levels
Specifically, null variants of the GSTM1 and GSTT1 alleles contain large deletions, and individuals who inherit two copies of the GSTM1 -null or GSTT1 -null alleles cannot produce the corresponding GST enzymes (54)
Animal studies and limited human trials suggest this can produce a mild GLP-1 response, though the effect size remains significantly smaller than pharmaceutical GLP-1 agonists
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