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Last reviewed: June 6, 2026 Last updated: June 6, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Acknowledgements The authors would like to thank all the participants, investigators and trial site staff who were involved in the conduct of the trials

This decision should always be made in consultation with a qualified healthcare provider

Challenges and Future Prospects Despite promising findings, GLP-1RAs face limitations in addiction treatment

CLA and L-carnitine each have plausible roles in the way the body handles fat, and combining them is reasonable on mechanistic grounds