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Weight-related biomarkers such as leptin and adiponectin may shift as body composition changes, reflecting the metabolic benefits beyond the scale
The body then flushes out the expelled fat-cell contents via the lymphatic system or burns them for energy
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For longevity physicians, this marks a fundamental shift from reactive to proactive medicine, requiring a new model where daily biomarker tracking informs real-time, precision-driven interventions
Timelines vary based on individual metabolic response, adherence, and clinical parameters, reinforcing the importance of personalized oversight
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