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When prescribed off-label for weight loss, patients often cover out-of-pocket costs

van Gorkom BA, de Vries EG, Karrenbeld A, Kleibeuker JH (1999) Review article: anthranoid laxatives and their potential carcinogenic effects

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This receptor activation results in: Rapid, pulsatile increases in GH secretion Amplification of sleep-related GH peaks Synergistic interaction with Growth Hormone-Releasing Hormone (GHRH) pathways The end result is elevated circulating levels of GH and IGF-1 , which support muscle growth, fat metabolism, and tissue repair