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When 5GABA-A receptor PAM, MP-III-022 was used in rats in the VPA model, an increase in mRNA level of KCC2 was observed only in females treated with a dose of 1 mg/kg, while the mRNA level of Gabra5 and Nkcc1 remained unchanged across doses and animal sexes [58]
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Distinguish the following disease states associated with inborn errors of metabolism, including (A) the deficient enzyme, (B) inheritance pattern of the disease, and (C) relation of the deficiency to the buildup of secondary metabolites
The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1
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