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To our knowledge, tissue NFT concentrations have not yet been determined in specific human organs
Blunted serotonin-mediated activation of the hypothalamic-pituitary-adrenal axis in chronic fatigue syndrome
But the study authors named it explicitly as an off-target activity they are working to engineer out, and even speculated that some of the glucose-tolerance benefit might come from it
Endocr Rev 16 : 143163 Mayo LD, Donner DB (2001) A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
Notably, Gurczynski et al
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