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The excessive weight gain further fuels the disease by worsening insulin resistance, dyslipidemia, hypertension, and pancreatic a-cell failure, resulting in a downward spiral [2]

The workaround many prescribers use: if a non-diabetic patient also has a comorbidity that a GLP-1 drug treats (cardiovascular disease for Wegovy, sleep apnea for Zepbound), the prescriber can request coverage under that indication

Finally, since Wegovy mimics the GLP-1 hormone, it may influence bodily fluid and potentially impact tear production

A licensed provider evaluates the patient, and eligible prescriptions are filled either as branded FDA-approved GLP-1 products or as compounded semaglutide or tirzepatide through a 503A pharmacy

Incretins are part of the internal physiologic system of glucose homeostasis regulation