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The 2004 Bissett study in International Journal of Cosmetic Science used twice-daily 5 percent niacinamide for 12 weeks in 50 women aged 40 to 60, documenting significant reductions in fine lines, hyperpigmentation spots, blotchiness, and yellowing [13]
Xu K, Shimelis H, Linn DE, Jiang R, Yang X, Sun F, et al
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doi: 10.1038/s41590-021-00913-5 89 HuangY.LiuX
Expert Tips for Brighter, More Even Skin Be consistent: Use your face wash daily
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