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While we know the gut microbiome dictates everything from our immunity to our mood, modern life think stress, travel, processed foods, and poor sleep constantly throws that delicate ecosystem out of whack

PloS one 4 (12), e8380

Furthermore, exendin-4 can stimulate the cyclic adenosine monophosphate/protein kinase A (cAMP-PKA) pathway by activating GLP-1R, which then increases the level of non-phosphorylated -catenin to stimulate the Wnt/-catenin/NeuroD1 pathway and inhibits the activity of GSK-3, ultimately decreasing the hyperphosphorylation of AD-associated tau proteins regulated by GSK-3 (Reich and Hlscher, 2022)

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Each link is individually defensible as a hypothesis and individually unproven as a conclusion about the blend