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doi: 10.1016/j.diabres.2012.09.008 210 WenjingHShaoYYuYHuangWFengGLiJ
Tamanna, N
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While Novo Nordisk currently has a number of additional GLP-1 drugs in the pipeline, including those that can be ingested and those that leverage both GLP-1 and Amylin agonists to offer better efficacy, Wegovy and Ozempic remain the company's primary offerings for now to treat obesity and diabetes
Common strategies to extend the duration of GLP-1 RAs include: Amino Acid Sequence Optimization: Reducing rapid degradation by DPP-4 enzymes to prolong the drugs half-life
Usually, this is a cardiac abnormality that results in either diastolic or systolic ventricular dysfunction (e.g., myocardial infarction or coronary artery disease)
