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The sensitivity of response rates to small dose differences was also evident for Esketamine, where a study in geriatric patients was ineffective overall, an outcome that might have been related to starting older patients on a low ineffective dose of 28 mg
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40 In the Copenhagen Heart Study, which tracked 12,000 participants for 21 years, high cholesterol was the 6th most relevant risk factor for developing CHD in both men and women
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