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The American journal of clinical nutrition, 89(3), 815821
Diabetologia 47:20592071
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However, PKA-activity appears to be essential for optimal incretin effects on stimulating insulin vesicle exocytosis." 5 There have been studies performed in animal subjects that show evidence of the pleiotropic effects of GLP-1 on beta cells such as beta cell regeneration and proliferation
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This mechanistic difference suggests they may have complementary effects when studied in laboratory settings, potentially affecting different aspects of the tissue repair process
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