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Consistent with murine ILC2s, melatonin increased human ILC2 expression of GCLC, the rate-limiting enzyme in glutathione synthesis, as well as NRF2 ( Figures 8B, C )
Structure-based discovery and bio-evaluation of a cyclopenta[4,5]thieno[2,3-: D] pyrimidin-4-one as a phosphodiesterase 10A inhibitor
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