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That event is tied to the DAC version , which keeps GH levels elevated for days
In the phase 2 randomised controlled trial (Jastreboff et al., New England Journal of Medicine , 2023), participants receiving higher doses of retatrutide achieved mean weight reductions of up to 17.5% of body weight over 24 weeks, with greater losses reported at 48 weeks
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It affects the signals between the gut and the brain that help control hunger, so you may not feel as driven to eat as often
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