Jamaluddin MS, Weakley SM, Yao Q, Chen C
Food and Drug Administration (FDA) hasnt approved any weight loss patches that work like the blockbuster injected GLP-1 drugs Ozempic, Wegovy, Zepbound, and Mounjaro, says Jody Dushay, MD, an assistant professor at Harvard Medical School and an endocrinologist at Beth Israel Deaconess Medical Center in Boston
GLP-1 receptors in the hypothalamus and brainstem modulate hunger and satiety signaling
The DAPA-HF, EMPEROR-REDUCED, EMPEROR-Preserved, DELIVER and other trials mentioned above consistently demonstrate the efficacy of SGLT-2i in patients with HF, regardless of LVEF or the presence of diabetes
In PCOS, where insulin resistance affects 50-70% of individuals, GLP-1 medications may help improve fasting glucose levels, reduce androgen production, and support metabolic regulation