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Many pharmaceutical companies have decided that the benefits outweigh the risks
Clinical trials show gastrointestinal side effects (nausea, vomiting, constipation) affect 20-40% of users across semaglutide, tirzepatide, and retatrutide, but severity and persistence vary widely
The clearest early signs are lower fasting blood sugar readings and more stable energy throughout the day
"In-person use is popular at chain stores such as CVS or Walgreens and at big box stores such as Walmart or Target," says Rami Sneineh, a licensed insurance producer and vice president of Insurance Navy
* **Constipation:** Difficulty passing stools
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