Supporting this, a recent prospective cohort study has confirmed that significant iron deposition in the caudate nucleus and putamen of patients with T2DM is significantly associated with diminished cognitive performance, manifesting as slower processing speed, declined memory, and poorer executive function, thereby indicating a negative correlation between the degree of iron accumulation in these nuclei and overall cognitive ability (Cheng et al., 2025)
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These positive inotropic effects of glucagon were diminished by a GLP1-R antagonist, by a GIPR antagonist, and by a CGCR antagonist but not by propranolol, an antagonist at -adrenoceptors