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Long-Term Considerations and Chronic Use Because obesity is a chronic condition requiring ongoing management, orforglipron will likely be used for years or even decades by many patients

Based on these findings, LY3298176, the dual GIP and GLP-1 receptor agonist, demonstrated superior efficacy in glucose control and weight loss compared to dulaglutide

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The Role of GLP-1 Medications in Menopause-Related Weight Gain GLP-1 receptor agonists like semaglutide work by mimicking glucagon-like peptide-1, a natural hormone that signals fullness to the brain, slows stomach emptying, and improves insulin sensitivity